The main symptom of this error is easily recognizable as you click on Outlook icon it start hanging for a while and then you start getting an error message Cannot Start Microsoft Office Outlook.
According to Microsoft major reason behind this issue is corruption in Navigation pane setting file profilename.xml, where profilename is name of Outlook profile. A good implication that file is damaged is when its size is 0KB. No one now the exact reason behind this error but it found in all version of Microsoft Outlook from 2003 to 2013.
Other apprehension may be you run Outlook in compatibility mode, or your profile is created in older Outlook version, or Outlook data file (.pst or .ost) was corrupted or deleted as the result of inaccurate Outlook uninstallation.
Anyway, whatever reason is outcome is same – you cannot open Outlook window because of the error Cannot start Microsoft Outlook, "Cannot open Outlook window, The set of folders cannot be opened."
In most cases corrupt navigation pane setting prevent Outlook from starting, so first you need to repair it. Learn how to do it on different operation system.
Note: Enter space between outlook.exe and /resetnavpane
If you wish to work with Run dialog on Windows 7 or 8, then follow given below steps
If due to some reason you are not able to recover Navigation pane configuration file, nor automatic fix equip by Microsoft work, try to delete XML file that stores navigation pane settings.
Steps to Delete Navigation pane setting
If you have resinstalled MS Outlook and went wrong at the time of previous version uninstallation, the default pst might have been corrupted or deleted. And due to which Outlook won't open.
Let's try Inbox Repair Tool (scanpst.exe) for outlook.pst
In Outlook 2013 and 2010 PST file found in Document/Outlook files folder. If you upgrade version of Outlook to 2010 then at such instant you will find an outlook.pst file in a hidden folder in given below location.
During Repair process a backup file is created at your machine. To change default name or location of backup file, enter new name in enter name of backup file or click on browse to look for file you want to use.
In Folder List, you see a folder by the name of Recovered Personal Folder that contains default Outlook folders or Lost and Found folder. Usually recover folders are empty, because this is a rebuilt file. Lost and Found folder caries the items recovery by scanpst.exe, items missing from Lost and Found folder cannot be repaired.
Alternatively find outlook.exe in default installation folder C:\Program Files\Microsoft Office\Office version
If still cannot open Outlook window and getting the same error Cannot start Microsoft Office Outlook then try to restore previous version of PST file. Of course in this situation some emails will be lost, but it seem better alternative than no Outlook. So right click on Outlook.pst file and select the Restore previous versions.
Create new Outlook profile if repairing and restoring Outlook.pst file process do not worked. If it does then copy the current Outlook data file (.pst) from broken profile to the new one.
Create new Outlook profile by following the given below steps:
If old pst file contains important data that you cannot live without, try third-party tool to recover PST file e.g Outlook PST Recovery.
Staring Outlook in safe mode means that it will be run without add-ins that is installed on machine. It is the fastest technique to found out is the Outlook start up problem is caused due the add-ins.
To start Outlook in safe mode, click on its icon holding Ctrl key or click on Start and enter outlook/safe in search line and press Enter. MS Outlook will display a message about the confirmation of starting Outlook in safe mode, click Yes.
An alternative way use outlook.exe / noextensions command, which means same start Outlook without any extensions.
If Outlook start in safe mode then definitely the problem is with one of the add-ins. So try to disable add-in one at a time to detect which one is causing the issue.
This problem most occurs in Office 2013/Office 365 but it may occur in Outlook 2010 and below versions. Main symptom is hanging Outlook on Loading Profile and main cause is clash between Original Equipment Manufacturer video driver and operating system.
To fix issue implement the following things:
The solution addresses above are considered as a most frequent reason of MS Outlook not starting. Hope it helps you.